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[Acne].

Ante Karoglan1,2, Harald P M Gollnick3

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Summary
This summary is machine-generated.

Acne vulgaris, a common skin condition affecting 85% of people, involves sebum, keratin, inflammation, and microbiome changes. Effective treatment requires addressing psychological impacts alongside medical care.

Keywords:
Acneiform eruptionsMental healthQuality of lifeSelf conceptStage-appropriate treatment

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Area of Science:

  • Dermatology
  • Microbiology
  • Psychology

Background:

  • Acne vulgaris is a prevalent dermatological condition with an 85% lifetime prevalence.
  • Pathogenesis involves increased sebum production, follicular hyperkeratinization, inflammation, and skin microbiome dysbiosis.
  • Both endogenous (hormonal) and exogenous (diet, cosmetics) factors influence acne development.

Purpose of the Study:

  • To provide a comprehensive overview of acne vulgaris, encompassing its pathogenesis, clinical variations, and psychological impact.
  • To highlight the multifactorial nature of acne, including hormonal influences, microbiome alterations, and external triggers.
  • To emphasize the importance of a holistic approach to acne management, integrating medical and psychological considerations.

Main Methods:

  • Review of current literature on acne vulgaris pathogenesis and clinical presentation.
  • Analysis of factors contributing to acne, including sebum production, keratinization, inflammation, and microbial imbalance.
  • Exploration of the psychological effects associated with acne and their impact on quality of life.

Main Results:

  • Acne vulgaris presents a wide clinical spectrum, from neonatal to adult forms, and varying severity.
  • Key pathogenic factors include hormonal imbalances, follicular hyperkeratinization, inflammatory responses, and skin dysbiosis.
  • Psychological distress and reduced quality of life are significant consequences of acne.

Conclusions:

  • Acne vulgaris is a complex condition influenced by multiple factors, requiring comprehensive management.
  • Effective acne therapy necessitates addressing both the physical manifestations and the profound psychological effects.
  • Integrated care, including regular medical follow-up and psychological support, is crucial for improving patient outcomes and quality of life.