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Agreement of intraocular lens power calculation between 2 SS-OCT-based biometers
Oliver A Pfaeffli1, Adrian Weber, Kenneth J Hoffer
1From the Department of Ophthalmology, Cantonal Hospital of Lucerne, Lucerne, Switzerland (Pfaeffli, Weber, Baenninger, Thiel, Müller); Stein Eye Institute, University of California, Los Angeles, California (Hoffer); St. Mary's Eye Center, Santa Monica, California (Hoffer); Fondazione G.B. Bietti I.R.C.C.S., Rome, Italy (Savini); Eye Clinic, S. Orsola-Malpighi University Hospital, University of Bologna, Bologna, Italy (Taroni).
Purpose:
To assess agreement of measurements by 2 swept-source optical coherence tomography biometers and to evaluate the prediction error (PE) in intraocular lens power calculation with 7 formulas.
Setting:
Tertiary public eye hospital.
Design:
Consecutive observational.
Methods:
Axial length (AL), keratometry (K), anterior chamber depth (ACD), lens thickness (LT), and corneal diameter (CD) were measured with the IOLMaster 700 (Biometer A) and Anterion (Biometer B). Agreement was quantified by the limits of agreement and concordance correlation coefficient (CCC). The PE, the median absolute error, and the mean absolute error of the Barrett Universal II, EVO 2.0, Haigis, Hoffer Q, Holladay 1, Kane, and SRK/T formulas were investigated after constant optimization.
Results:
In 78 eyes from 78 patients, excellent agreement was obtained for AL (CCC >0.99), very good agreement for K, ACD, and LT (CCC >0.95), and strong agreement for CD (CCC >0.72). An additive offset of 0.07 mm was measured for ACD and LT whose mean values were higher with Biometer B (P < .001). No statistically significant difference was found between the PEs and their absolute values when comparing the results of each formula between the 2 biometers.
Conclusions:
Agreement of biometric measurements by the 2 biometers was high, although Biometer B provided higher mean values of ACD and LT by 0.07 mm. In cataract patients with normal eye length, measurements by the 2 biometers did not lead to different refractive outcomes with the 7 formulas investigated.
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