Related Experiment Video
Updated: Oct 23, 2025
08:56
Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies
Published on: October 7, 2021
2.9K
Mononeuropathy Multiplex After COVID-19.
Nathan Carberry1, Helen Badu1, Christina M Ulane1
1Department of Neurology.
Journal of Clinical Neuromuscular Disease
|August 25, 2021
Summary
COVID-19 infection is linked to mononeuropathy multiplex, a rare peripheral nervous system disorder causing asymmetric sensorimotor loss. This study details four cases, suggesting a potential connection for future treatment considerations.
Area of Science:
- Neurology
- Infectious Diseases
- Peripheral Neuropathy
Background:
- COVID-19 (coronavirus disease 2019) has emerged as a significant global health crisis.
- While central nervous system (CNS) neurological manifestations of COVID-19 are documented, peripheral nervous system (PNS) involvement remains less explored.
- Systemic neuropathies following COVID-19 infection require further investigation.
Observation:
- This study observed four patients who developed mononeuropathy multiplex after contracting COVID-19.
- These patients presented with asymmetric sensorimotor deficits characteristic of peripheral neuropathy.
- The onset of neuropathy occurred subsequent to severe COVID-19 infection.
Findings:
- The study details the clinical history, COVID-19 disease course, and diagnostic evaluations for the four patients.
- Mononeuropathy multiplex was diagnosed in all cases following COVID-19 infection.
- The findings highlight a potential association between COVID-19 and this specific type of peripheral neuropathy.
Implications:
- A potential link between COVID-19 and mononeuropathy multiplex is postulated.
- Understanding this association may inform prognostication and rehabilitation strategies for affected patients.
- Further research into the pathomechanisms could lead to novel therapeutic interventions for post-COVID-19 neuropathy.
More Related Videos
Related Concept Videos
01:27Myocarditis II: Clinical Features and Diagnostic Tests
49
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
49
01:21Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
76
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
76
01:24Local Anesthetics: Differential Sensitivity of Nerve Fibers
1.1K
Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
1.1K
01:15Myasthenia Gravis: Diagnostic Tests
1.5K
Myasthenia gravis is an autoimmune condition affecting neuromuscular transmission, causing generalized weakness in skeletal muscles. Initial diagnoses rely on patients' signs, symptoms, and medical history. The challenge lies in distinguishing myasthenia from other muscular dystrophies. An important diagnostic feature is the significant improvement of symptoms after administering anticholinesterase inhibitors.
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
1.5K
01:30Peripheral Artery Disease I: Introduction
79
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
79
01:28Major Somatic Sensory Pathways
1.4K
Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the...
1.4K