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Updated: Oct 22, 2025

A Protocol for Analyzing Hepatitis C Virus Replication
Published on: June 26, 2014
Training to Cure-Implementing a Hepatitis C Clinic Curriculum in Primary Care Residency Training
Yihan Yang1, Jeffrey M Luk2, Andre N Sofair1
1Section of General Internal Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT USA.
Background:
Residents lack exposure to chronic hepatitis C (HCV) infection management, limiting the pipeline of providers able to alleviate the treatment bottleneck.
Activity:
We surveyed 34 residents rotating through a new HCV curriculum comprised of a clinic primer, didactics, and supervised patient care. Outcome measures were knowledge and self-efficacy regarding HCV management.
Results:
HCV knowledge scores improved significantly from 58% pre-clinic to 76% immediately post (p < 0.001)- and 66% 3-month post-clinic (p = 0.006). Residents felt more confident managing HCV after the clinic rotation.
Discussion:
Our clinic curriculum is feasible, improves knowledge regarding HCV, and is a unique approach to preparing physicians to cure HCV.
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