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Eosinophilic Colitis in Recurrent Sigmoid Volvulus
Kelly Zucker1, Faruq Pradhan1, Adam Gomez2
1Department of Gastroenterology, Carl T. Hayden VA Medical Center, Phoenix, Arizona.
ACG Case Reports Journal
|September 3, 2021
Summary
Eosinophilic colitis is a rare gut inflammation where eosinophils infiltrate the intestines. This case highlights its variable presentation, linking it to recurrent volvulus with eosinophilic findings.
Area of Science:
- Gastroenterology
- Pathology
Background:
- Eosinophilic colitis (EC) is part of a spectrum of eosinophilic gastrointestinal disorders (EGIDs).
- EGIDs involve eosinophil infiltration of the gastrointestinal tract without other known causes of tissue eosinophilia.
- EC is the least common of the primary EGIDs, alongside eosinophilic esophagitis and eosinophilic gastritis.
Observation:
- Eosinophilic colitis presents with highly variable inflammation.
- Inflammation can affect the mucosal, submucosal, and transmural layers of the gut.
- This case involved recurrent volvulus.
Findings:
- The patient's recurrent volvulus exhibited histologic findings of eosinophilia.
- This suggests a potential link between EC and volvulus.
Implications:
- Recognizing the variable presentations of EC is crucial for diagnosis.
- This case broadens the understanding of potential clinical manifestations of EC.
- Further research may elucidate the relationship between eosinophilic inflammation and gastrointestinal obstruction like volvulus.
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