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Updated: Oct 20, 2025

Studying Orthodontic Tooth Movement in Mice
Published on: August 2, 2024
[PRIMARY DIAGNOSTICS AND ORTHODONTIC TREATMENT PLANNING FOR PATIENTS ON MEDICINAL REGIMEN FOR CONCOMITANT
1Moscow State University of Medicine and Dentistry named of A.I. Yevdokimov, Russia.
Abstract:
In everyday practice orthodontists treat a lot of patients with different general diseases or taking some medications and nutritional supplements. Many farmacological agents and pathological conditions could influence bone metabolism and deteriorate the results of orthodontic therapy. Aim of the study was to analyze how many orthodontic patients have general diseases of taking any medications on regular basis. To work out diagnostic and treatment algorithms, based on general health status of the patient. 273 questionaries of orthodontic patients, treated by the same doctor in private clinic were analyzed. 97 patients (age 3,5-18 years) and 176 patients (age 19-64). 39,9% of patients have one or more chronic diseases (allergy, hypofunction of thyroid gland, artritis, hypertension, osteoporosis, diabetes II type). 60,4% of patients take on regular basis estrogen-containing medications, L-thyroxine, glucocorticoid therapy, NSAI medications, vitamin D₃, Omega-3 and other nutritional supplements. Knowledge of clinical signs of the general disease, understanding of pathological process and it possible influence on the physiology of orthodontic tooth movement are of paramound importance for the orthodontist to work out correct treatment plan, choose type of appliance, schedule of activation and retention protocol.
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