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Essential Oils as Alternative Promising Anti-Candidal Agents: Progress and Prospects
Awad Shala1, Shweta Singh2, Saif Hameed2
1Medicinal and Aromatic Plants Research Department, Horticulture Research Institute, Agricultural Research Center, Giza 12619,Egypt.
Current Pharmaceutical Design
|September 15, 2021
Summary
Essential oils from medicinal plants show promise as natural antifungal agents against Candida species. This review explores their potential as safer, eco-friendly alternatives to conventional antibiotics.
Area of Science:
- Mycology
- Pharmacology
- Ethnobotany
Background:
- Candida albicans is a major cause of opportunistic fungal infections.
- Increasing antifungal resistance and side effects of conventional drugs necessitate alternative treatments.
- Medicinal plants offer a source of bioactive compounds, including essential oils, with therapeutic potential.
Purpose of the Study:
- To review the antifungal efficacy of essential oils against Candida species.
- To highlight essential oils as potential alternatives to conventional antifungal drugs.
- To provide recommendations for future research and development of new antifungal formulations.
Main Methods:
- Literature review of studies investigating essential oils and their anti-Candida activity.
- Analysis of reported antimicrobial, anti-inflammatory, and antioxidant properties of essential oils.
- Synthesis of data on the efficacy of various essential oils against Candida spp.
Main Results:
- Essential oils exhibit potent antimicrobial properties against Candida species.
- These natural compounds demonstrate lower toxicity and better biodegradability compared to synthetic drugs.
- Essential oils possess anti-inflammatory and antioxidant activities beneficial for treating fungal infections.
Conclusions:
- Essential oils are promising natural candidates for combating fungal infections caused by Candida.
- Further clinical studies are required to develop novel therapeutic formulations.
- Medicinal plant-derived essential oils offer a sustainable and effective alternative to current antifungal treatments.
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