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[Hypertension after kidney transplantation]
Nora Schwotzer1, Grégoire Wuerzner1, Déla Golshayan2
1Service de néphrologie et d'hypertension, Département de médecine, CHUV, 1005 Lausanne.
Revue Medicale Suisse
|September 16, 2021
Summary
Post-kidney transplant hypertension is common and impacts long-term outcomes. This review covers its causes, prevalence, and management strategies for better cardiovascular and graft survival.
Area of Science:
- Nephrology
- Cardiology
- Transplantation Medicine
Background:
- Kidney transplantation is the preferred treatment for end-stage renal disease.
- While immunosuppression improves graft survival, cardiovascular complications remain a concern.
- Arterial hypertension is highly prevalent after kidney transplantation.
Purpose of the Study:
- To review the epidemiology of post-transplant hypertension.
- To discuss the multifactorial causes of hypertension after kidney transplantation.
- To outline current management strategies and blood pressure targets.
Main Methods:
- Literature review of studies on hypertension post-kidney transplantation.
- Analysis of factors contributing to hypertension, including traditional risks, allograft-related issues, and immunosuppressive drugs.
- Examination of current guidelines and evidence for blood pressure targets.
Main Results:
- Hypertension is a frequent complication affecting long-term prognosis.
- Causes include traditional risk factors, allograft function/anatomy, and immunosuppressive agents.
- Evidence for specific blood pressure targets (<130/80 mmHg) and their impact is limited.
Conclusions:
- Effective management of hypertension is crucial for improving cardiovascular and graft outcomes.
- Further research is needed to establish optimal blood pressure targets.
- A comprehensive approach addressing all contributing factors is essential.
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