[Care course of a potential living kidney donor]

Care course of a potential living kidney donor. Care course of a potential living kidney donor is quite long (about 1-3 months) and sometimes cumbersome. During the first visit we evaluate the donor's motivations, and we look for potential medical contraindications such as recent neoplasia treatment, chronic viral infections (hepatitis B, C or HIV), and uncontrolled hypertension despite 2 hypotensive drugs. At the end of that consultation some lab tests are performed: serum creatinine (and eGFR), microalbuminuria, ABO and HLA typings. At the same time the recipient will be ABO and HLA typed as well as being tested for anti-HLA antibodies. The second step within the donor will be to perform renal angioCT scan in order to detect potential surgical contraindications. At this point the donor will meet the surgeon, and if it is fine he will undergo specific exams such as measurement of glomerular filtration rate (iohexol clearance), echocardiography and ambulatory blood pressure monitoring (if indicated). Females will undergo mammography, cervical smear and pelvic echography, whereas males will be tested for PSA. At this point a multidisciplinary team will validate (or not) the medical project. If it is the case the medical files are transmitted to the Agence de la biomédecine, which will then send them to the expert committee (5 members). The latter will give an unmotivated answer.