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Related Concept Videos

Vaccinations01:51

Vaccinations

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Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics01:23

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Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla.  Benzonatate operates peripherally within the respiratory tract by...
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Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

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The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
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Teratogenicity01:07

Teratogenicity

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The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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Pharmacokinetics: Drug–Food and Drug–Viral Interactions01:26

Pharmacokinetics: Drug–Food and Drug–Viral Interactions

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A drug interaction occurs when the concurrent use of another drug, food, or an external substance alters the pharmacological activity of a drug. This interaction can modify the action of the original drug, affecting its effectiveness and safety.Drug–food interactions are significant as they impact drug absorption, metabolism, and excretion. For example, grapefruit juice is a well-known disruptor of drug metabolism. It inhibits the cytochrome P450 3A4 enzyme, crucial for the metabolism of...
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Transmission-based Precautions I: Contact, Enteric, and Droplets01:17

Transmission-based Precautions I: Contact, Enteric, and Droplets

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Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
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Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
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Covid-19, Pregnancy, and Vaccinations.

Nola A Holness1, Yolanda M Powell-Young2, Elisa Torres3

  • 1Nicole Wertheim College of Nursing and Health Sciences, Florida International University, AHC-3 Room 323, 1200 SW 8th Street, Miami, FL 33199 nholness@fiu.edu.

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Pregnant individuals with COVID-19 face higher risks of severe illness. COVID-19 vaccination is crucial for this high-risk group, yet data on vaccine safety in pregnancy is limited.

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coronavirus diseasemorbiditypregnancysafetyvaccination

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Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Vaccinology

Background:

  • Pregnancy with COVID-19 elevates risks for severe illness, hospitalization, and need for life support.
  • Pregnant women were excluded from initial COVID-19 vaccine trials, creating a data gap on safety and efficacy.
  • Contradictory vaccination recommendations for pregnant individuals necessitate urgent data dissemination.

Purpose of the Study:

  • To highlight the critical need for COVID-19 vaccine safety data in pregnant populations.
  • To address the gap in scientific understanding regarding vaccine use in pregnancy.
  • To inform public health strategies for protecting pregnant women from COVID-19.

Main Methods:

  • Review of existing scientific literature on COVID-19 in pregnancy.
  • Analysis of available data on COVID-19 vaccine safety profiles (mRNA and viral vector).
  • Assessment of current vaccination guidelines and recommendations for pregnant women.

Main Results:

  • Pregnant women with COVID-19 experience increased morbidity and mortality.
  • Current COVID-19 vaccines are believed to be safe for obstetrical and neonatal outcomes.
  • Significant inconsistencies exist in current vaccination recommendations for pregnant individuals.

Conclusions:

  • Urgent collation and dissemination of vaccine safety data are essential for pregnant women.
  • Vaccination is a key strategy to prevent severe COVID-19 illness in this high-risk group.
  • Addressing data gaps will advance the health and wellness of pregnant individuals and their neonates.