Related Experiment Video
Updated: Oct 18, 2025

Cryosectioning Method for Microdissection of Murine Colonic Mucosa
Published on: July 12, 2015
The Isolated Mucosa of the Rat Colon Decellularization, Microscopy and Cell Cultures
Pedro Mestres-Ventura1, Laura López Gómez2, Gilberto Del Rosario Hernández3
1Department of Anatomy and Cell Biology, Faculty of Medicine, Saarland University, 66421, Homburg Saar, Germany. pedro.mestres@uks.eu.
Abstract:
This project presents the most important findings of the studies, which we carried out in our laboratory on the decellularization of the rat isolated colonic mucosa. We have also included some details of the experiences gathered with the muscle layer as well as the whole wall of the colon. The question of the cytocompatibility of this new substrate has been addressed with the application of primary cultures of human cells and well-established cell lines. The possible applications in experimental and medical settings will be discussed.

