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Updated: Oct 18, 2025

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
Conduction Disturbances and Pacing in Transcatheter Aortic Valve Replacement
Makoto Nakashima1, Hasan Jilaihawi1
1Heart Valve Center, NYU Langone Health, 530 1st Avenue, Suite 9V, New York, NY 10016, USA.
Abstract:
Conduction disturbances (CDs) after transcatheter artic replacement remain a clinical concern and relatively common complication. A recent meta-analysis showed both new-onset persistent left bundle branch block and new permanent pacemaker implantation were related to all-cause death with risk ratio 1.32 (95% confidence interval [CI] 1.17 to 1.49; P<.001) and 1.17 (95% CI 1.11-1.25; P<.001) at 1 year, respectively. Preprocedural computed tomography imaging can highlight potential risk factors for CDs, such as membranous septum length, device landing zone calcium, and the annulus size/degree of device oversizing.
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