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Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
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Neurologic Complications in Transcatheter Aortic Valve Replacement
Abel Ignatius1, Marvin H Eng1, Tiberio M Frisoli2
1Center for Structural Heart Disease, Henry Ford Hospital, 2799 W Grand Boulevard, Detroit, MI 48202, USA.
Interventional Cardiology Clinics
|October 1, 2021
Summary
Transcatheter aortic valve replacement (TAVR) is standard for severe aortic stenosis. Despite improvements, stroke rates remain high, with key risk factors including older age and atrial fibrillation needing further study.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Neurology
Background:
- Transcatheter aortic valve replacement (TAVR) is a primary treatment for severe symptomatic aortic stenosis.
- While TAVR complication rates have decreased, stroke incidence remains persistently high.
- TAVR-related strokes impose significant burdens on patients, families, and healthcare systems.
Purpose of the Study:
- To review and define the predictors of stroke following TAVR.
- To identify patient and procedural factors associated with increased stroke risk.
Main Methods:
- Systematic review of existing literature on TAVR-related stroke.
- Analysis of identified risk factors across multiple studies.
Main Results:
- Stroke rates after TAVR have not significantly improved despite advancements.
- Emerging risk factors for TAVR-related stroke include older age, female gender, comorbidities like peripheral arterial disease, bicuspid aortic valve anatomy, and atrial fibrillation.
Conclusions:
- Understanding TAVR stroke predictors is crucial for improving patient outcomes.
- Further research is needed to mitigate stroke risk in TAVR patients.
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