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Microbial inhibition and biosensing with multifunctional carbon dots: Progress and perspectives
Moorthy Maruthapandi1, Arumugam Saravanan1, Poushali Das1
1Department of Chemistry, Bar-Ilan Institute for Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat-Gan 52900, Israel.
Biotechnology Advances
|October 8, 2021
Summary
Carbon dots (CDs) and nitrogen-doped CDs (N@CDs) show promise as antimicrobial agents and in sensing applications due to their unique properties. These nanomaterials offer potential for advancements in biotechnology, including medical devices and therapies.
Area of Science:
- Nanomaterials Science
- Biotechnology
- Analytical Chemistry
Background:
- Carbon dots (CDs) and nitrogen-doped CDs (N@CDs) are emerging 2D carbon-based nanosized materials.
- They possess advantageous properties such as biocompatibility, ease of preparation, aqueous dispersibility, and multifunctionality.
Purpose of the Study:
- To review the antimicrobial, optical, and electrochemical properties of CDs and N@CDs.
- To explore their applications in bacterial eradication, sensing, and biosensing.
- To discuss current challenges and future prospects of CDs in pathogenesis and analytics.
Main Methods:
- Synthesis of CDs and N@CDs via bottom-up or top-down approaches.
- Characterization of their functional groups (hydroxyl, carboxyl, amino).
- Evaluation of antimicrobial, optical, and electrochemical properties.
Main Results:
- CDs and N@CDs exhibit antimicrobial activity by generating free radicals.
- They function as photoluminescent nanomaterials for diverse analytics.
- Their surface groups enable the development of sensors, biosensors, and nanocomposites.
Conclusions:
- CDs and N@CDs are versatile nanomaterials with significant biotechnological potential.
- Their applications span bacterial eradication, advanced sensing, and therapeutic interventions.
- Future directions include microbial viability assays, wound healing, antiviral therapy, and medical devices.
