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Updated: Oct 17, 2025

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
Published on: January 5, 2018
[Recommendations for management of misuses and addictions to benzodiazepines]
Carole Grandjean1, Séverine Crettol Wavre2, Yasser Khazaal3,4
1Pharmacien·ne·s, Unité de pharmacogénétique et de psychopharmacologie clinique, Centre de neurosciences psychiatriques, Département de psychiatrie, CHUV et Université de Lausanne, 1008 Prilly.
Abstract:
The management of patients who have become dependent on benzodiazepines and analogues is a problem frequently encountered in both somatic and psychiatric medicine. No pharmacological treatment is currently recognized as effective in the management of these addictions, apart from a gradual reduction of doses. We propose practical strategies for the implementation of gradual dose reduction and choice of molecules while promoting individual adaptation to the withdrawal symptoms presented by the patient.
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