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Updated: Oct 16, 2025
Magnetic Resonance Elastography Methodology for the Evaluation of Tissue Engineered Construct Growth
Published on: February 9, 2012
Comparative analysis of the quantitative parameter method and elasticity color mode method for real-time shear wave
Shan-Shan Xue1, Qiao-Ling Zhao1, Li-Tao Ruan1
1Department of Ultrasound, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shanxi, China.
Objective:
To examine the performance of real-time shear wave elastography (RT-SWE) in routine clinical practice.
Methods:
This was a prospective study of 500 patients. The elasticity color mode method was judged by a four-mode system. The quantitative parameter method was used to measure the modulus of elasticity of the lesions. Pathologic reports were used as a gold standard to comparatively analyze the diagnostic performance of the two methods.
Results:
A total of 553 tumors were detected. The average mode value and the modulus of elasticity (Emax) of the benign breast masses was lower than that of malignant masses (p < 0.05). With Emax = 67.4 as the diagnostic threshold value, the sensitivity, specificity, accuracy, negative predictive value, and positive predictive value of the two methods were not statistically significant different (p > 0.05).
Conclusions:
The shear wave quantitative parameter method and the elasticity color mode method showed similar performances in the diagnosis of benign and malignant breast masses. The elasticity color mode method is convenient and intuitive, whereas the quantitative parameter method can be used to objectively assess the lesions when it is difficult to score the elasticity of an image, but could not be relied on alone.
