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Iterative denoising accelerated 3D SPACE FLAIR sequence for brain MR imaging at 3T
Michael Eliezer1, Alexis Vaussy2, Solenn Toupin2
1Department of Neuroradiology, Lariboisiere University Hospital, 75010 Paris, France; Université de Paris, Faculté de Médecine, 75010 Paris, France.
Diagnostic and Interventional Imaging
|October 19, 2021
Summary
High acceleration factors in 3D-FLAIR MRI reduce scan times by 37% without compromising image quality. This technique, using iterative denoising (ID), maintains excellent visualization of deep brain nuclei and white matter/gray matter differentiation for brain tumor patients.
Area of Science:
- Radiology and Medical Imaging
- Neuroimaging
- Magnetic Resonance Imaging (MRI)
Background:
- Three-dimensional fluid-attenuated inversion recovery (3D-FLAIR) sequences are crucial for brain MRI.
- High acceleration factors can reduce scan times but may impact image quality.
- Iterative denoising (ID) algorithms show promise in enhancing image quality in accelerated MRI.
Purpose of the Study:
- To prospectively evaluate the image quality of 3D-FLAIR MRI at 3-T using a high acceleration factor combined with iterative denoising (ID).
- To compare image quality, deep brain nuclei visualization, and white matter/gray matter differentiation between conventional FLAIR and accelerated FLAIR with and without ID.
Main Methods:
- Thirty brain tumor patients underwent 3-T MRI with two 3D-FLAIR sequences: conventional FLAIR (acceleration factor 6) and accelerated FLAIR (acceleration factor 9).
- Accelerated FLAIR images were reconstructed both with (acc-FLAIR-ID) and without (acc-FLAIR) iterative denoising.
- Two neuroradiologists assessed image quality, deep brain nuclei visualization, and WM/GM differentiation using a 4-point scale.
Main Results:
- Scanning time was reduced by 37% for acc-FLAIR-ID and acc-FLAIR compared to conv-FLAIR (4 min 40 sec vs. 2 min 50 sec).
- Image quality scores were significantly higher for both conv-FLAIR and acc-FLAIR-ID compared to acc-FLAIR.
- WM/GM differentiation and deep brain nuclei visualization scores were comparable between conv-FLAIR and acc-FLAIR-ID, while both were superior to acc-FLAIR.
Conclusions:
- Utilizing a high acceleration factor with iterative denoising for 3D-FLAIR MRI significantly reduces scanning time by 37%.
- This accelerated technique preserves diagnostic image quality, including white matter/gray matter differentiation and deep brain nuclei visualization.
- Accelerated 3D-FLAIR with ID is a viable option for efficient brain MRI in patients with brain tumors.
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