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Updated: Oct 16, 2025

Author Spotlight: Transmitochondrial Cybrid Generation Using Cancer Cell Lines
Published on: March 17, 2023
Mitochondria and the Tumour Microenvironment in Blood Cancer
Jamie A Moore1, Jayna J Mistry1,2, Stuart A Rushworth3
1Department of Molecular Haematology, Norwich Medical School, University of East Anglia, Norwich, UK.
Abstract:
The bone marrow (BM) is a complex organ located within the cavities of bones. The main function of the BM is to produce all the blood cells required for a normal healthy blood system. As with any major organ, many diseases can arise from errors in bone marrow function, including non-malignant disorders such as anaemia and malignant disorders such as leukaemias. This article will explore the role of the bone marrow, in normal and diseased haematopoiesis, with an emphasis on the requirement for intercellular mitochondrial transfer in leukaemia.
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