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Updated: Oct 16, 2025
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A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion
Published on: November 12, 2020
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Case Report: Retinal Infarction Associated with Migraine.
William S Slagle, Savannah R Sheets1, Amy B Logan2
1Western Carolina Eye Associates, Jefferson, North Carolina.
Summary
Migraine episodes can cause temporary vision loss due to retinal ischemia. Optical coherence tomography revealed unique retinal changes, suggesting a potential link to migrainous infarction in the retina.
Area of Science:
- Ophthalmology
- Neurology
- Medical Imaging
Background:
- Retinal migraine and migrainous infarction are distinct clinical entities.
- Migraine-associated visual disturbances require further investigation into their underlying pathophysiology.
Observation:
- A case of profound monocular vision loss during a migraine episode is presented.
- Optical coherence tomography (OCT) revealed acute inner retinal thinning and increased signal intensity in the photoreceptor layer.
- These OCT findings were observed across different retinal vascular territories.
Findings:
- The observed OCT features are distinct from those seen in retinal artery occlusions and other primary ocular vasculopathies.
- The retinal changes suggest acute inner retinal ischemia.
- This case provides potential clinical evidence of retinal migrainous infarction.
Implications:
- This case highlights the utility of OCT in visualizing retinal changes associated with migraine.
- Understanding these changes may lead to improved diagnosis and management of visual disturbances in migraine patients.
- Further research is warranted to confirm the link between these OCT findings and migrainous infarction.
