Acute monocytic leukemia presenting in the eyelid. An immunohistochemical and electron microscopic study

A 28-year-old woman was evaluated for a firm subcutaneous nodule of the left upper eyelid. Results from the examination showed multiple red to brown subcutaneous nodules on her upper extremities and thorax. An excisional biopsy specimen showed the nodules to be cutaneous involvement of acute monocytic leukemia. Acute monocytic leukemia should be considered in the differential diagnosis of a subcutaneous nodule in the eyelid.