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Updated: Oct 15, 2025

Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid
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Microneedling for Hair Loss.

Aditya K Gupta1,2, Emma M Quinlan1, Maanasa Venkataraman1

  • 1Mediprobe Research Inc., London, ON, Canada.

Journal of Cosmetic Dermatology
|October 29, 2021
PubMed
Summary

Microneedling therapy shows promise for androgenetic alopecia (AGA). It significantly increased hair count compared to minoxidil alone, and combination therapy further enhanced results. Further research is needed for monotherapy efficacy.

Keywords:
acneandrogenetic alopeciahair lossmale pattern baldnessmicroneedling

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Area of Science:

  • Dermatology
  • Regenerative Medicine

Background:

  • Microneedling, a minimally invasive technique using fine needles, is a novel therapy for dermatological conditions.
  • It is increasingly explored for treating androgenetic alopecia (AGA).

Purpose of the Study:

  • To synthesize existing literature on microneedling in dermatology.
  • To evaluate the efficacy of microneedling for AGA using quantitative analysis of clinical trials.

Main Methods:

  • Comprehensive literature review of microneedling studies.
  • Linear multivariable regression analysis for evidence synthesis.
  • Quality assessment of studies included in quantitative analysis.

Main Results:

  • Microneedling monotherapy significantly increased hair count more than topical minoxidil 5%.
  • Combination therapy with microneedling and topical minoxidil 5% yielded greater hair count increase than microneedling alone.
  • Longer treatment duration and reduced session frequency may enhance hair count increase.

Conclusions:

  • Microneedling shows promising preliminary results for AGA treatment.
  • Limited studies exist on microneedling as monotherapy; most trials combine it with minoxidil or PRP.
  • Larger, randomized controlled trials are necessary to establish microneedling's safety, efficacy, and role in AGA treatment.