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Rapid differential diagnosis of the B.1.617.2 (delta) variant of SARS-CoV-2 using an automated Cas12a-microfluidic
Pintao Li1, Jin Zhang2, Qiuyuan Lin1
1Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, P. R. China. fxech@fudan.edu.cn.
Chemical Communications (Cambridge, England)
|November 9, 2021
Abstract:
An automated Cas12a-microfluidic system was constructed to distinguish the B.1.617.2 (delta) variant of SARS-CoV-2 from the wild-type virus rapidly and was validated using 30 clinical samples, showing 100% consistency with next-generation sequencing. It will be a potential tool for the rapid differential diagnosis of the delta variant of SARS-CoV-2.
