Related Experiment Video

Updated: Oct 13, 2025

Transmission Electron Microscopy as the Visualization Technique for Analysis of Circadian Synaptic Plasticity in the Mouse Barrel Cortex
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Transmission Electron Microscopy as the Visualization Technique for Analysis of Circadian Synaptic Plasticity in the Mouse Barrel Cortex

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Astrocyte Circadian Timekeeping in Brain Health and Neurodegeneration

Marco Brancaccio1,2, Anne C Wolfes3,4, Natalie Ness3,4

  • 1Department of Brain Sciences, Division of Neuroscience, Imperial College London, London, UK. m.brancaccio@imperial.ac.uk.

Advances in Experimental Medicine and Biology
|November 13, 2021
PubMed
Summary

Astrocytes, a type of glial cell, are now understood to be circadian timekeepers that regulate daily rhythms. Altered astrocyte timekeeping may contribute to neurodegenerative diseases like Alzheimer's disease.

Keywords:
Alzheimer’s diseaseAstrocyte timekeepingCircadian clocksNeurodegenerationSleep

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