Related Experiment Video
Updated: Oct 12, 2025
07:24
Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
11.9K
Globicatella sanguinis corneal abscess with endophthalmitis
Barkha Gupta1, Arun K Jain1, Manu Saini1
1Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Summary
Globicatella sanguinis, a rare bacterium, caused a severe eye infection in a child after trauma. Prompt laboratory diagnosis and antibiotic sensitivity testing were crucial for effective treatment.
Area of Science:
- Ophthalmology
- Microbiology
- Infectious Diseases
Background:
- Globicatella sanguinis is a rare bacterium.
- It typically affects the bloodstream, urinary tract, and central nervous system.
Observation:
- A 9-year-old boy presented with a corneal abscess and endophthalmitis after eye trauma.
- The infection was identified as Globicatella sanguinis.
Findings:
- Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) enabled rapid identification.
- Vitek 2 system determined the antibiotic sensitivity profile.
Implications:
- This case underscores the importance of considering rare pathogens in post-traumatic ocular infections.
- Advanced laboratory techniques are vital for diagnosing and managing infections caused by atypical microorganisms.
- Early and accurate diagnosis facilitates appropriate antimicrobial therapy and improves patient outcomes.
Related Concept Videos
01:25Glaucoma: Overview
959
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
959
01:28Angle Closure Glaucoma: Treatment
886
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
886
01:25Endocarditis I: Introduction
58
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
58
01:25Endocarditis II: Clinical Features of Infective Endocarditis
45
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
45