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Related Concept Videos

Sutures of the Skull01:22

Sutures of the Skull

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The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
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Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
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Cranial Bones: Superior and Posterior View01:14

Cranial Bones: Superior and Posterior View

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The superior view of the cranium shows the frontal and paired parietal bones.
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
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Related Experiment Video

Updated: Oct 12, 2025

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
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Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

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Syndromic Craniosynostosis: Unique Management Considerations.

David S Hersh1, Christopher D Hughes2

  • 1Division of Neurosurgery, Connecticut Children's, 282 Washington Street, Hartford, CT 06106, USA; Department of Surgery, UConn School of Medicine, 200 Academic Way, Farmington, CT 06032, USA.

Neurosurgery Clinics of North America
|November 21, 2021
PubMed
Summary
This summary is machine-generated.

Syndromic craniosynostosis requires specialized care due to increased intracranial pressure risks. Management involves a multidisciplinary team and surgical interventions like fronto-orbital advancement.

Keywords:
ApertCraniosynostosisCrouzonMuenkePfeifferSaethre–ChotzenSyndromic

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Area of Science:

  • Craniofacial surgery
  • Pediatric neurosurgery
  • Genetics

Background:

  • Craniosynostosis is the premature fusion of cranial sutures.
  • It can be isolated (nonsyndromic) or part of a syndrome.
  • Syndromic craniosynostosis presents unique management challenges.

Purpose of the Study:

  • To outline key considerations for managing syndromic craniosynostosis.
  • To highlight the importance of a multidisciplinary approach.
  • To review surgical management options.

Main Methods:

  • Review of current clinical practices and literature.
  • Emphasis on multidisciplinary team coordination.
  • Discussion of surgical techniques.

Main Results:

  • Syndromic craniosynostosis necessitates close monitoring for intracranial hypertension.
  • A coordinated craniofacial team is crucial for comprehensive care.
  • Surgical options include vault remodeling, posterior expansion, endoscopic suturectomy, and midface advancement.

Conclusions:

  • Effective management of syndromic craniosynostosis relies on specialized, coordinated care.
  • Multidisciplinary teams and tailored surgical approaches are essential.
  • Vigilant monitoring is critical due to associated risks.