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Microfluidic nanomaterials: From synthesis to biomedical applications.

Kavitha Illath¹, Srabani Kar², Pallavi Gupta¹

¹Department of Engineering Design, Indian Institute of Technology Madras, India.

|November 21, 2021

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Microfluidic platforms enable precise nanomaterial synthesis for biomedical uses. This review highlights their role in automated screening and clinical evaluation of nanomaterials.

Area of Science:

Biomedical Engineering
Materials Science
Nanotechnology

Background:

Microfluidic platforms offer unique advantages for nanomaterial synthesis in biomedical research.
Automated screening of nanomaterials is crucial for developing advanced biomedical applications.

Purpose of the Study:

To critically evaluate the controlled synthesis of diverse nanomaterials using microfluidic devices.
To review microfluidic trends for tailoring nanomaterial properties (size, composition, morphology).
To emphasize the clinical evaluation of nanomaterials within microfluidic systems.

Main Methods:

Review of current literature on microfluidic platforms for nanomaterial synthesis.
Discussion of nanomaterial screening techniques and their automation.

Keywords:

Biomedical applications Clinical evaluations Microfluidics Nanomaterials Screening

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Analysis of microfluidic systems for simulating physiological conditions for nanomaterial evaluation.

Main Results:

Microfluidics facilitates the synthesis of various nanomaterials (noble metals, quantum dots, iron oxide, etc.) with controlled properties.
Nanomaterial screening in microfluidics enhances automation, speed, and repeatability.
Microfluidic systems enable in-vitro evaluation of nanomaterials under physiological conditions, crucial for clinical translation.

Conclusions:

Microfluidic technology is pivotal for the controlled synthesis and screening of nanomaterials for biomedical applications.
Microfluidics offers a unique platform for the clinical evaluation of nanomaterials, addressing a gap in current reviews.
Future directions include novel material development and expanded biomedical applications leveraging microfluidic capabilities.