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How much prestin motor activity is required for normal hearing?

Kazuaki Homma1, Satoe Takahashi2, Mary Ann Cheatham3

  • 1Department of Otolaryngology - Head and Neck Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA; The Hugh Knowles Center for Clinical and Basic Science in Hearing and Its Disorders, Northwestern University, Evanston, IL 60208, USA.

Hearing Research
|December 1, 2021
PubMed
Summary

Outer hair cell (OHC) motor protein prestin is crucial for hearing, but new research suggests cochlear function remains robust even with reduced prestin activity, challenging previous assumptions.

Keywords:
Cochlear amplificationElectromotilityOuter hair cellsPrestinSLC26A5

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