Machine Learning and Intracranial Aneurysms: From Detection to Outcome Prediction
Vittorio Stumpo1,2, Victor E Staartjes3, Giuseppe Esposito1
1Machine Intelligence in Clinical Neuroscience (MICN) Laboratory, Department of Neurosurgery, Clinical Neuroscience Center, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Acta Neurochirurgica. Supplement
|December 4, 2021
Summary
Machine learning (ML) shows promise in intracranial aneurysm (IA) research for detection and outcome prediction. While ML models outperform traditional methods, clinical application remains limited.
Area of Science:
- Biomedical Sciences
- Medical Imaging
- Artificial Intelligence
Background:
- Machine learning (ML) offers advanced capabilities for data analysis in biomedical research.
- Intracranial aneurysms (IA) present complex diagnostic and prognostic challenges.
- Traditional statistical methods have limitations in handling large, complex medical datasets.
Purpose of the Study:
- To review the application of ML in intracranial aneurysm (IA) research.
- To assess the performance of ML models in IA detection, rupture prediction, and outcome assessment.
- To evaluate the potential of ML in improving IA patient management.
Main Methods:
- Review of studies applying ML algorithms, including convolutional neural networks, to IA data.
- Analysis of ML model performance in tasks such as segmentation, classification, and prediction.
- Comparison of ML approaches with traditional statistical methods and expert analysis.
Main Results:
- ML models, particularly convolutional neural networks, demonstrate high sensitivity in IA detection, often exceeding expert performance.
- ML shows potential in differentiating ruptured from unruptured IAs and predicting rupture risk.
- ML-based prediction of complications and functional outcomes post-subarachnoid hemorrhage (SAH) is more established than for unruptured IA procedures.
Conclusions:
- Machine learning holds significant potential to revolutionize intracranial aneurysm patient management.
- Current clinical translation of ML in IA research is limited, indicating a need for further development and validation.
- ML algorithms offer superior performance over conventional methods for various IA-related predictive tasks.
Related Concept Videos
Aneurysm III: Interprofessional Care
50
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
50
Aneurysm II: Clinical Manifestations and Diagnostic Studies
46
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
46

