Acquired cutis laxa type II (Marshall syndrome) in a 3-month-old boy

Tekumalla Sindhuja1, Narayanan Arunachalam1, Vishal Gupta1

  • 1Departments of Dermatology and Pathology, All India Institute of Medical Sciences, New Delhi, India.

Pediatric Dermatology
|December 20, 2021
PubMed

Insights

Acquired cutis laxa type II, a rare elastolysis, presents treatment challenges. Early intervention during the inflammatory phase is crucial for managing this condition in infants and children.

Area of Science:

  • Dermatology
  • Pediatric Medicine
  • Genetics

Background:

  • Acquired cutis laxa type II (Marshall syndrome) is a rare elastolytic disorder.
  • This condition typically manifests in infancy and childhood.
  • Effective treatment options for acquired cutis laxa type II are limited.

Observation:

  • A case study involving a 3-month-old boy is presented.
  • The patient exhibited acquired cutis laxa type II.
  • The condition was secondary to a neutrophilic dermatosis.

Findings:

  • Acquired cutis laxa type II can arise secondary to neutrophilic dermatosis.
  • The initial inflammatory phase of the dermatosis is critical.
  • Prompt treatment of inflammation may prevent permanent skin damage.

Implications:

  • Early diagnosis and treatment of neutrophilic dermatosis are vital in pediatric cases.
  • Aggressive management of the inflammatory phase can mitigate the severity of acquired cutis laxa type II.
  • This case highlights the importance of addressing underlying inflammatory conditions to prevent elastolysis.

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