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Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing
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Injectable wireless microdevices: challenges and opportunities.
Adam Khalifa1, Sunwoo Lee2, Alyosha Christopher Molnar2
1Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. akhalifa1@mgh.harvard.edu.
Bioelectronic Medicine
|December 23, 2021
Summary
Injectable wireless microdevices, smaller than 0.5mm, offer a stable and safe way to monitor health and interface with the nervous system, transforming healthcare.
Area of Science:
- Biomedical Engineering
- Materials Science
- Neuroscience
Background:
- Significant advancements in wireless implantable medical devices over three decades.
- Current devices offer physiological monitoring and nervous system interfacing, transforming healthcare.
- Need for more stable, safe, effective, and distributed interfaces drives innovation.
Purpose of the Study:
- To review state-of-the-art fully injectable wireless microdevices.
- To discuss injection techniques for these microdevices.
- To address current challenges and future opportunities in this field.
Main Methods:
- Review of recent advances in micro/nanofabrication techniques.
- Analysis of novel powering and communication methodologies.
- Examination of device miniaturization to sub-millimeter scales.
Main Results:
- Development of wireless implantable devices at the scale of dust (<0.5mm).
- Enabling full injection of devices with minimal insertion damage.
- Progress in creating stable, safe, and effective microscale interfaces.
Conclusions:
- Injectable wireless microdevices represent a new class of implantable devices.
- These microdevices have the potential for widespread application in healthcare.
- Further development is needed to overcome current challenges and realize future opportunities.
