Related Experiment Video

Updated: Oct 9, 2025

Murine Echocardiography of Left Atrium, Aorta, and Pulmonary Artery
08:17

Murine Echocardiography of Left Atrium, Aorta, and Pulmonary Artery

Published on: February 20, 2017

14.6K

Echocardiographic Structure and Function in Elderly Patients With Atrial Fibrillation in Japan　- The ANAFIE

Ken-Ichi Hiasa1, Hidetaka Kaku1, Goro Kawahara1

  • 1Kyushu University.

Circulation Journal : Official Journal of the Japanese Circulation Society
|December 23, 2021
PubMed

Insights

Elderly patients with atrial fibrillation (AF) and heart failure (HF) often show left atrial (LA) enlargement and impaired function. These findings highlight the cardiac structural and functional impact of AF and HF in older populations.

Area of Science:

  • Cardiology
  • Geriatrics
  • Echocardiography

Background:

  • Limited echocardiographic data exists for elderly patients with atrial fibrillation (AF) and heart failure (HF).
  • The ANAFIE Registry subcohort study aimed to characterize cardiac structure and function in this population.

Purpose of the Study:

  • To analyze echocardiographic parameters in elderly patients with AF and HF.
  • To identify specific cardiac structural and functional characteristics associated with these conditions.

Main Methods:

  • Analysis of echocardiographic data from 1,494 elderly patients within the ANAFIE Registry.
  • Assessment of left atrial (LA) volume, LA reservoir function, mitral and tricuspid regurgitation, and left ventricular (LV) parameters.

Main Results:

  • Half of the patients exhibited severe LA enlargement (≥48 mL/m²), strongly correlating with impaired LA reservoir function.
  • AF type and rhythm significantly impacted LA volume and function.
  • History of HF was associated with more frequent moderate-to-severe mitral/tricuspid regurgitation and higher early diastolic mitral inflow velocity to mitral annulus velocity ratio.

Conclusions:

  • Left atrial enlargement and dysfunction are prevalent in elderly patients with non-valvular AF and a history of HF.
  • These patients also demonstrated increased LV mass index, reduced LV ejection fraction, and elevated heart rate.
Abstract

Keywords:
Atrial fibrillationEchocardiographyElderlyHeart failureLeft atrial function

More Related Videos

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation08:10

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Published on: July 20, 2022

1.8K
Evaluation of Left Ventricular Structure and Function using 3D Echocardiography06:34

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

Published on: October 28, 2020

4.2K

Related Concept Videos

Imaging Studies for Cardiovascular System I:Echocardiography01:17

Imaging Studies for Cardiovascular System I:Echocardiography

Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...
512
Imaging Studies for Cardiovascular System II:Types of Echocardiography01:20

Imaging Studies for Cardiovascular System II:Types of Echocardiography

Echocardiography plays a role in assessing cardiac health and detecting heart conditions, with various types providing critical insights for diagnosis and treatment.
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...
415
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
96
Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
72
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
40
Dysrhythmias V: Evaluating Dysrhythmias01:30

Dysrhythmias V: Evaluating Dysrhythmias

Dysrhythmias, also known as arrhythmias, are disturbances in the heart's rhythm that range from benign to life-threatening. A thorough evaluation is crucial for appropriate management and involves a comprehensive medical history, physical examination, and various diagnostic tests.Medical HistorySymptoms: Collect detailed information on palpitations, dizziness, syncope, chest pain, and fatigue. Note their onset, frequency, and triggers.Previous Cardiac Issues: Document any history of heart...
139