Related Experiment Video
Updated: Oct 7, 2025

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
Published on: June 7, 2015
Accuracy evaluation of surface registration algorithm using normal distribution transform in stereotactic body
Haenghwa Lee1, Jeong-Mee Park1, Kwang Hyeon Kim1
1Department of Neurosurgery, Neuroscience, & Radiosurgery Hybrid Research Center, Inje University Ilsan Paik Hospital, College of Medicine, Goyang, Republic of Korea.
The Normal Distribution Transform (NDT) algorithm offers superior surface registration accuracy for stereotactic body radiotherapy (SBRT) and stereotactic radiosurgery (SRS) compared to the Iterative Closest Point (ICP) method. NDT provides more reliable surface model, reposition, and target accuracy in optical imaging systems.
Area of Science:
- Medical Physics
- Radiotherapy Technology
- Image Registration
Background:
- Surface registration is crucial for accurate patient positioning in stereotactic body radiotherapy (SBRT) and stereotactic radiosurgery (SRS).
- Traditional methods like the Iterative Closest Point (ICP) algorithm have limitations in achieving optimal accuracy.
- Novel algorithms are needed to enhance precision in image-guided radiation therapy.
Purpose of the Study:
- To evaluate the feasibility and performance of the Normal Distribution Transform (NDT) algorithm.
- To compare NDT with the Iterative Closest Point (ICP) method for surface registration accuracy in SBRT/SRS.
- To determine the clinical utility of NDT in optical imaging systems for radiotherapy.
Main Methods:
- Point cloud images were acquired using a depth camera-based optical imaging (OSI) system.
- Surface registration was performed using both NDT and ICP algorithms.
- Registration error and root-mean-square (RMS) values were calculated for surface model, reposition, and target accuracy, with statistical analysis using a paired t-test.
Main Results:
- NDT demonstrated significantly lower registration errors and RMS values for surface model accuracy compared to ICP (p < 0.05).
- NDT also showed superior performance in reposition accuracy, with reduced average error and RMS values (p = 0.005).
- Overall target accuracy improved with NDT, reducing reposition error and RMS by 0.71 mm and 1.32 mm, respectively (p = 0.03).
Conclusions:
- The Normal Distribution Transform (NDT) algorithm provides more reliable accuracy for surface model, reposition, and target accuracies than the Iterative Closest Point (ICP) method.
- NDT is a feasible and accurate surface registration algorithm for optical imaging systems in SBRT/SRS.
- NDT offers a promising advancement for improving precision in image-guided radiotherapy procedures.

