Related Experiment Video
Updated: Oct 7, 2025

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
Published on: January 7, 2019
Effectiveness of peer support interventions for adults with depressive symptoms: a systematic review and
Shefaly Shorey1, Joelle Yan Xin Chua1
1Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Background:
Many adults suffer from depression and peer support has been shown to reduce depressive symptoms.
Aim:
To examine the effectiveness of peer support interventions for adults with depressive symptoms.
Methods:
Five electronic databases were searched until February 2021. A random-effect meta-analysis was conducted. The I2 statistics and Cochran's Q chi-squared test assessed heterogeneity. Quality appraisal was conducted by the Cochrane risk of bias tool and the Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) approach at the study and outcome level, respectively.
Results:
Seventeen studies conducted in most Western countries and on the maternal population were included. Three types of peer support interventions (peer-delivered psychotherapy, individualized peer mentoring, and peer support group discussions) were identified. Significant effects of peer support interventions were found when compared to standard care. However, professional-led psychotherapy and exercise programs showed more effectiveness compared to peer support group discussions.
Conclusions:
Future trials could be improved by engaging trained healthy peers (peers with and without prior history of depression) to deliver interventions, encouraging online methods of communication between participants and peers, and facilitating the building of deeper connections between participants and peers. Considering the low-quality rating by the GRADE approach, future research is needed to corroborate current findings.
Related Concept Videos
Self-Help Support Groups
Accessibility and Cost-Effectiveness
One of the primary strengths of self-help...
Depressive Disorders: MDD and Dysthymia
Depression: Overview
Treatment Strategies for Psychological Disorders
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Stress Prevention and Stress Management Techniques V

