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Updated: Oct 6, 2025
Fluorescence Lifetime Imaging of Molecular Rotors in Living Cells
Published on: February 9, 2012
Novel cationic meso-CF3 BODIPY-based AIE fluorescent rotors for imaging viscosity in mitochondria
Wen-Jing Shi1, Jinrong Yang2, Yong-Feng Wei1
1School of Chemistry and Chemical Engineering, Guangzhou University, Guangzhou 510006, P. R. China. swj114@gzhu.edu.cn.
Abstract:
Two novel meso-CF3 BODIPY-based fluorescent rotors have been rationally prepared and found to sensitively respond to viscosity in living cells with a fluorescence "turn-on" effect, attributed to the special restricted rotation of meso-CF3 group in viscous environments. Interestingly, a monostyryl probe with one cationic group exhibits good mitochondrial localization and AIE property.
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