RAS at 40: Update from the RAS Initiative
Dwight V Nissley1, Frank McCormick2
1Frederick National Laboratory for Cancer Research, Frederick, Maryland.
Cancer Discovery
|January 20, 2022
Summary
The RAS Initiative aims to develop new therapies for KRAS-driven cancers, addressing critical unmet patient needs. This collaborative effort unites researchers to advance treatment options for these challenging malignancies.
Area of Science:
- Oncology
- Molecular Biology
- Drug Discovery
Background:
- KRAS-driven cancers represent a significant unmet clinical need.
- Targeting RAS pathways is crucial for effective cancer therapy.
Purpose of the Study:
- To establish and coordinate a research initiative focused on RAS-driven cancers.
- To foster collaborations for the development of novel RAS therapies.
Main Methods:
- The RAS Initiative was launched in 2013.
- It is based at Frederick National Laboratory for Cancer Research.
- It involves collaborations with academic and industry researchers.
Main Results:
- The initiative has brought together a diverse research community.
- Progress has been made in understanding RAS biology and identifying therapeutic targets.
Conclusions:
- The RAS Initiative is actively working towards developing new treatments for patients with KRAS-driven cancers.
- Continued collaboration is essential for advancing RAS-targeted therapies.
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