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Related Experiment Video

Updated: Oct 6, 2025

The Submerged Printing of Cells onto a Modified Surface Using a Continuous Flow Microspotter
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Advances in Single-Cell Printing.

Xiaohu Zhou1, Han Wu1, Haotian Wen1

  • 1Shenzhen Bay Laboratory, Institute of Cell Analysis, Shenzhen 518132, China.

Micromachines
|January 21, 2022
PubMed
Summary
This summary is machine-generated.

Single-cell printing offers precise deposition and high efficiency for isolating individual cells. This review highlights advanced bioprinting strategies and their applications in biological research.

Keywords:
cell arrayinkjet printingmicrofluidicsscreeningsingle-cell analysis

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Area of Science:

  • Biotechnology
  • Cell Biology
  • Bioengineering

Background:

  • Single-cell analysis is crucial for modern biological and medical research.
  • Effective single-cell isolation is a prerequisite for accurate single-cell analysis.
  • Single-cell printing emerges as a superior technique due to its precision, efficiency, and ease of recovery.

Purpose of the Study:

  • To review recent advancements in bioprinting strategies with single-cell resolution.
  • To focus specifically on inkjet-like single-cell printing technologies.
  • To explore diverse applications and future prospects of single-cell printing.

Main Methods:

  • Review of current literature on single-cell printing techniques.
  • Categorization of common and advanced cell printing strategies.
  • Analysis of applications including single-cell array screening, mass spectrometry, and 3D tissue formation.

Main Results:

  • Inkjet-like single-cell printing offers precise deposition and high encapsulation efficiency.
  • Single-cell printing enables applications from high-throughput screening to complex tissue engineering.
  • Various printing strategies demonstrate distinct advantages and limitations.

Conclusions:

  • Single-cell printing is a rapidly advancing field with significant potential in biological and medical research.
  • Further development of single-cell printing technologies will enhance single-cell analysis capabilities.
  • The review provides insights into the pros, cons, and future outlook of single-cell printing strategies.