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Related Experiment Video

Updated: Oct 5, 2025

Innovative Adipose Tissue Fractionation for Transforming Fat into Specialized Components
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Study of a New Controlled Focal Septa Release Cellulite Reduction Method.

W Grant Stevens1, Michael S Kaminer, Sabrina G Fabi

  • 1University of Southern California, Keck School of Medicine, Marina del Rey, CA.

Aesthetic Surgery Journal
|January 28, 2022
PubMed
Summary
This summary is machine-generated.

A new minimally invasive technique effectively treats cellulite by precisely releasing connective tissue bands. This safe and feasible method significantly improves the appearance of moderate to severe cellulite in women.

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Area of Science:

  • Dermatology
  • Minimally Invasive Procedures
  • Aesthetic Medicine

Background:

  • Cellulite, a common skin condition, causes dimpling on the buttocks and thighs, often leading to emotional distress.
  • A novel minimally invasive method was previously shown to be safe and feasible for precise cellulite treatment.

Purpose of the Study:

  • To evaluate the safety, efficacy, and feasibility of a new minimally invasive cellulite treatment.
  • To assess the method's effectiveness in reducing moderate to severe cellulite in adult women.

Main Methods:

  • An open-label, multicenter study enrolled 20 women aged 21-55 with moderate to severe cellulite.
  • Patients were assessed at multiple time points up to 180 days post-treatment.
  • The primary endpoint was a significant reduction in the Cellulite Severity Scale.

Main Results:

  • 95% of patients achieved the primary endpoint of improved cellulite severity.
  • 100% of patients showed marked or very marked improvement.
  • Reported adverse events were mild, transient, and not unexpected.

Conclusions:

  • The novel minimally invasive method is safe and effective for improving moderate to severe cellulite.
  • This precise septa-releasing technique benefits women across various skin types.