Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Pharyngitis01:23

Chronic Pharyngitis

5.9K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
5.9K
Sputum Studies I: Gram Stain, cytology, and Acid-fast smear and culture01:26

Sputum Studies I: Gram Stain, cytology, and Acid-fast smear and culture

314
Sputum studies are a critical part of diagnosing and treating numerous respiratory conditions. These studies involve obtaining sputum samples for analysis to identify pathogenic organisms and assess the presence of abnormal cells indicative of malignant conditions. This lesson will delve into three fundamental sputum studies: Gram Stain, Cytology, and Acid-fast Smear and Culture.
Gram Stain
The Gram Stain is an integral part of sputum studies. It involves the staining of sputum, which permits...
314
Acute Pharyngitis01:30

Acute Pharyngitis

1.9K
Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
1.9K
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

133
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
133
Sputum Studies II: Culture and Sensitivity01:20

Sputum Studies II: Culture and Sensitivity

669
Description
Sputum culture and sensitivity is a medical procedure used to diagnose bacterial infections in the respiratory tract and select the most appropriate antibiotics for treatment. This process involves analyzing sputum samples of thick and opaque secretions produced in the lungs and airways. These samples are collected from patients and then sent to the laboratory for analysis.
The test can identify various pathogens responsible for respiratory infections, including Streptococcus,...
669
Tonsillitis I: Introduction01:30

Tonsillitis I: Introduction

660
Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
660

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Optimization of the magnetic difference calibration method on Huan Liu-3 tokamak.

The Review of scientific instruments·2026
Same author

Endoplasmic Reticulum-Mitochondria Calcium Drives Salivary Bioenergetics.

Journal of dental research·2026
Same author

[Cellular prion protein expression and its correlation with pathological features in colorectal cancer].

Zhonghua bing li xue za zhi = Chinese journal of pathology·2026
Same author

[Research advances in drug repurposing strategies for synergistic sensitization of colorectal cancer immunotherapy​].

Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery·2025
Same author

Multi-scale Interaction Mechanism for Edge-Localized-Mode Suppression in the Tokamak Edge.

Nature communications·2025
Same author

[Advances in thyroid cytopathology in China over the last ten years: retrospect and prospect].

Zhonghua bing li xue za zhi = Chinese journal of pathology·2025

Related Experiment Video

Updated: Oct 3, 2025

Standardization of Basket Use in Sialendoscopy: A Ten-Year Retrospective Study
09:36

Standardization of Basket Use in Sialendoscopy: A Ten-Year Retrospective Study

Published on: June 6, 2025

261

[Studies on newly recognized chronic sialadenitis].

G Y Yu1,2, D G Liu3, W Li1

  • 1Department of Oral & Maxillofacial Surgery, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key laboratory of Digital Stomatology, Beijing 100081, China.

Beijing Da Xue Xue Bao. Yi Xue Ban = Journal of Peking University. Health Sciences
|February 15, 2022
PubMed
Summary

New classifications for chronic sialadenitis, including IgG4-related sialadenitis (IgG4-RS) and eosinophilic sialodochitis (ES), offer specific treatments. Radioiodine-induced sialadenitis (RAIS) requires prevention strategies. These advances improve diagnosis and management of salivary gland diseases.

Keywords:
Eosinophilic sialodochitisIgG4-related sialadenitisParotid glandRadioactive iodine-induced sialadenitisSalivary glandSubmandibular gland

More Related Videos

Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients
05:26

Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients

Published on: March 1, 2024

1.3K
Author Spotlight: A Focus on Standardized Salivary Gland Ultrasound Protocol in Connective Tissue Disease Research
07:25

Author Spotlight: A Focus on Standardized Salivary Gland Ultrasound Protocol in Connective Tissue Disease Research

Published on: October 13, 2023

3.3K

Related Experiment Videos

Last Updated: Oct 3, 2025

Standardization of Basket Use in Sialendoscopy: A Ten-Year Retrospective Study
09:36

Standardization of Basket Use in Sialendoscopy: A Ten-Year Retrospective Study

Published on: June 6, 2025

261
Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients
05:26

Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients

Published on: March 1, 2024

1.3K
Author Spotlight: A Focus on Standardized Salivary Gland Ultrasound Protocol in Connective Tissue Disease Research
07:25

Author Spotlight: A Focus on Standardized Salivary Gland Ultrasound Protocol in Connective Tissue Disease Research

Published on: October 13, 2023

3.3K

Area of Science:

  • Salivary gland pathology
  • Immunology
  • Oncology
  • Allergy

Background:

  • Chronic sialadenitis encompasses diverse conditions with distinct etiologies and clinical presentations.
  • Recent years have seen the recognition of specific subtypes, including IgG4-related sialadenitis (IgG4-RS), radioiodine-induced sialadenitis (RAIS), and eosinophilic sialodochitis (ES).
  • These conditions necessitate tailored diagnostic and therapeutic approaches beyond conventional obstructive sialadenitis (COS).

Purpose of the Study:

  • To present a novel classification of chronic sialadenitis based on recent findings.
  • To delineate the specific characteristics, pathogenesis, and treatment strategies for IgG4-RS, RAIS, and ES.
  • To emphasize the importance of distinguishing these entities from COS for effective patient management.

Main Methods:

  • Review of clinical, histopathological, and immunological data for IgG4-RS, RAIS, and ES.
  • Analysis of potential etiological factors, including occupational chemical exposure for IgG4-RS and 131I dosage for RAIS.
  • Comparison of diagnostic and therapeutic outcomes for these conditions versus conventional obstructive sialadenitis.

Main Results:

  • IgG4-RS, an immune-mediated disease, shows increased incidence linked to occupational chemical exposure; treatment involves glucocorticoids and steroid-sparing agents, not surgery.
  • RAIS, a complication of differentiated thyroid cancer treatment with 131I, presents with swelling and requires conservative management and prevention.
  • ES, an allergic inflammatory disease, is characterized by specific clinical and laboratory findings and managed with conservative and anti-allergic therapies, distinct from COS.

Conclusions:

  • A new classification of chronic sialadenitis is proposed, integrating IgG4-RS, RAIS, and ES.
  • Specific treatments are effective for IgG4-RS and ES, while RAIS management focuses on conservative care and prevention.
  • Recognizing these distinct entities is crucial for optimizing salivary gland disease diagnosis and treatment.