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Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection
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Graphene: A Promising Theranostic Agent.

S M Shatil Shahriar1, Md Nafiujjaman2, Jeong Man An3

  • 1Department of Cancer Research, College of Medicine, University of Nebraska Medical Center, Omaha, NE, USA.

Advances in Experimental Medicine and Biology
|February 17, 2022
PubMed
Summary

Graphene shows promise as a theranostic agent for targeted drug delivery due to its unique properties. Large-scale production methods are crucial for its widespread application in treating diseases like cancer.

Keywords:
Biomedical applications of grapheneGrapheneNext-generation graphene derivativesSynthesis of grapheneToxicity of graphene

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Area of Science:

  • Nanoscience
  • Biomedical Engineering
  • Materials Science

Background:

  • Graphene, a 2D carbon allotrope, is recognized for its exceptional photostability, solubility, and low toxicity.
  • Its nanoscale properties, including high biocompatibility and photoluminescence, drive interest in biomedical applications.
  • Current limitations in biomedical applications stem from challenges in achieving large-scale production.

Purpose of the Study:

  • To review synthesis methods for graphene production.
  • To explore the potential of graphene-based theranostic agents.
  • To address challenges in the clinical translation of graphene applications.

Main Methods:

  • Review of existing literature on graphene synthesis and applications.
  • Analysis of graphene's properties relevant to theranostics.
  • Discussion of challenges and future perspectives in graphene production and utilization.

Main Results:

  • Graphene exhibits significant potential as a theranostic agent for targeted drug and gene delivery.
  • Graphene-based systems show promise for treating various diseases, including cancer and Alzheimer's.
  • The development of scalable and cost-effective synthesis methods is critical for clinical adoption.

Conclusions:

  • Graphene's unique properties position it as a superior theranostic agent.
  • Further research into scalable production and toxicological profiles is essential for clinical translation.
  • Graphene-based therapies offer a promising avenue for advancing disease treatment.