Testicular Dysfunction Among Cancer Survivors
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Updated: Oct 2, 2025

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
Published on: March 6, 2018
Angel Elenkov1, Aleksander Giwercman1
1Department of Translational Medicine, Lund University, CRC; Jan Waldenströms gata 35, SE 214 28 Malmö, Sweden; Reproductive Medicine Centre, Skane University Hospital, Östra Varvsgatan 11F, SE 205 02 Malmö, Sweden.
Abstract:
In parallel with increased survival rates, quality of life (QoL) has become of growing importance in the management of young cancer survivors. Several surveys have indicated that in those subjects, the issue of reproductive function is considered as one of the main QoL aspects. In this article, we summarize the current evidence, as well as gaps of knowledge and research needs, regarding the impact of cancer and cancer treatment on testicular function-including fertility and androgen production. Also, pre and posttherapy clinical management of reproductive issues in male cancer survivors, are given.
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