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Celiac disease and the surgeon.

Jon S Thompson1, Peter Mannon2

  • 1Department of Surgery, University of Nebraska Medical Center, Omaha, NE, USA.

American Journal of Surgery
|February 28, 2022
PubMed
Summary

Celiac disease (CD) presents varied symptoms and is often missed by surgeons. Awareness of CD-related conditions and potential post-operative symptoms is crucial for diagnosis.

Keywords:
Celiac diseaseIntestinal malignancySurgery and celiac diseaseUnmasking celiac disease

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Area of Science:

  • Gastroenterology
  • Surgical Pathology

Background:

  • Celiac disease (CD) involves intestinal inflammation and villus atrophy.
  • CD has diverse clinical presentations and is increasingly diagnosed, yet often remains undiagnosed in surgical patients.

Purpose of the Study:

  • To review celiac disease aspects pertinent to surgical practice.
  • To enhance surgeon awareness of celiac disease and its surgical implications.

Main Methods:

  • A literature search of the PubMed database was conducted.
  • Articles published between January 2000 and December 2021 focusing on surgical issues in CD were reviewed.

Main Results:

  • Celiac disease is linked to various gastrointestinal conditions and an elevated risk of malignancies, including small intestinal tumors.
  • Patients with CD face increased risks for common surgical procedures like appendicitis.
  • Undiagnosed CD can manifest post-operatively, leading to diagnosis after surgery.

Conclusions:

  • Surgeons must recognize CD-associated conditions, malignancy risks, and confounding symptoms.
  • Post-operative development of malabsorptive symptoms warrants suspicion for undiagnosed celiac disease.