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Orthostatic blood pressure changes and diabetes duration
Juan F Idiaquez Rios1, Leif Erik Lovblom2, Bruce A Perkins3
1Ellen & Martin Prosserman Centre for Neuromuscular Diseases University Health Network, University of Toronto, Canada.
Journal of Diabetes and Its Complications
|March 21, 2022
Summary
Orthostatic hypotension and hypertension are common in diabetic sensorimotor polyneuropathy (DSP). Longer diabetes duration is linked to orthostatic hypotension, while shorter duration is associated with orthostatic hypertension in DSP patients.
Area of Science:
- Cardiology
- Neurology
- Endocrinology
Background:
- Diabetic sensorimotor polyneuropathy (DSP) affects a significant number of diabetic patients.
- Autonomic dysfunction, including orthostatic dysregulation, is a known complication of diabetes.
Purpose of the Study:
- To investigate the prevalence of orthostatic hypotension (OH) and orthostatic hypertension (OHT) in patients with DSP.
- To identify clinical characteristics associated with OH and OHT in this population.
Main Methods:
- A retrospective cross-sectional study involving 200 DSP patients.
- Orthostatic vital signs (blood pressure and heart rate) were measured supine and after 3 minutes of standing.
Main Results:
- The prevalence of OH was 19.5% and OHT was 23% in the studied DSP cohort.
- Patients with OH had a significantly longer duration of diabetes compared to normotensive individuals and those with OHT.
- Blood pressure changes during orthostatic testing correlated with diabetes duration and age in patients with OH.
Conclusions:
- Both orthostatic hypertension and orthostatic hypotension are frequent findings in patients with diabetic sensorimotor polyneuropathy.
- Orthostatic hypertension appears to be associated with a shorter duration of diabetes compared to orthostatic hypotension.
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