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Updated: Sep 29, 2025

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
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Multi-Functional Hydrogel-Interlayer RF/NFC Resonators as a Versatile Platform for Passive and Wireless Biosensing.

Manik Dautta1, Muhannad Alshetaiwi1, Alberto Escobar2

  • 1Department of Electrical Engineering and Computer Science, University of California Irvine, Irvine, CA 92697, USA.

Advanced Electronic Materials
|March 21, 2022
PubMed
Summary
This summary is machine-generated.

New wireless sensors use hydrogel-interlayer radio-frequency resonators for passive, healthcare monitoring. These microelectronics-free devices offer wireless readout and cellphone compatibility for broad applications.

Keywords:
RFid sensorshydrogel electronicspassiveradio-frequencystretchablewearable sensorswireless

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Area of Science:

  • Materials Science
  • Electrical Engineering
  • Biomedical Engineering

Background:

  • Wearable sensors are crucial for monitoring human body state.
  • Existing sensors often lack essential features like passivity, wireless readout, and specificity for healthcare.
  • There is a need for advanced, accessible sensing technologies.

Purpose of the Study:

  • To demonstrate a versatile platform for passive and wireless biosensing using hydrogel-interlayer radio-frequency resonators.
  • To develop sensor systems compatible with standard mobile devices for easy data acquisition.
  • To create soft, conformable sensor skins for integrated human body monitoring.

Main Methods:

  • Fabrication of radio-frequency resonators using a vinyl cutter with hydrogel interlayers.
  • Tuning resonator sensitivity by modifying hydrogel composition for specific analytes or physical signals.
  • Integration of resonators with LEDs to form near-field communication (NFC) sensor circuits.
  • Assembly of resonator arrays into soft silicone sensor skins.

Main Results:

  • Demonstrated hydrogel-interlayer resonators as a passive, wireless sensing platform.
  • Enabled direct quantification of sensor state via cellphone and eye using NFC technology.
  • Developed soft, wireless sensor skins capable of co-reading analytical and physical signals.
  • Achieved low-cost, accessible sensor fabrication and integration.

Conclusions:

  • Hydrogel-interlayer radio-frequency resonators offer a promising, versatile solution for passive wireless biosensing.
  • The developed NFC-based sensor circuits and sensor skins are suitable for emerging healthcare applications.
  • This low-cost, accessible platform has transformative potential for integrated environmental and body monitoring.