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Refactory Coeliac disease-a case series from Pakistan
Tropical Doctor
|March 31, 2022
Summary
Coeliac disease, an autoimmune disorder triggered by gluten, often causes chronic diarrhoea and malabsorption. Refractory coeliac disease presents diagnostic and management challenges, as illustrated by three patient cases.
Area of Science:
- Gastroenterology
- Immunology
- Internal Medicine
Background:
- Coeliac disease (or gluten intolerance) is a common condition causing chronic diarrhoea and malabsorption.
- Refractory coeliac disease (RCD) is a rare complication, posing significant diagnostic and therapeutic difficulties.
Purpose of the Study:
- To present three challenging cases of refractory coeliac disease.
- To highlight the complexities in diagnosing and managing RCD.
Main Methods:
- Case report series.
- Review of clinical presentation, diagnostic workup, and treatment strategies for three patients with RCD.
Main Results:
- Detailed clinical and pathological findings for each of the three RCD cases.
- Varied responses to treatment and management approaches were observed.
Conclusions:
- Refractory coeliac disease requires a high index of suspicion for timely diagnosis.
- Multidisciplinary management is crucial for optimizing outcomes in RCD patients.
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