Related Experiment Video
Updated: Sep 27, 2025
Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
Published on: February 18, 2022
Quantitative Evaluation of Macular Vessel Density Measurement by Optical Coherence Tomography Angiography in Patients
Sirel Gür Güngör1, Almila Sarıgül Sezenöz1, Noor Adwan1
1Faculty of Medicine, Department of Ophthalmology, Başkent University, Ankara, Turkey.
Purpose:
To evaluate the macular vessel density (VD) in inactive ocular sarcoidosis (OS) and investigate the relationship between VD and both disease duration and visual acuity (VA).
Methods:
This cross-sectional study was performed at a tertiary hospital. The macular VDs of patients with OS were obtained using optical coherence tomography angiography and compared with healthy subjects.
Results:
Deep whole image macular VD (WI-MVD), parafoveal, and perifoveal VDs were lower in OS group (p = .01, p = .01, p = .02, respectively). Negative correlation between disease duration and both superficial and deep WI-MVD, parafoveal, and perifoveal VDs was obtained (for all p < .05). There was a positive correlation between VA and superficial VD (p < .001, r = 0.848 for WI-MVD).
Conclusion:
OS affects deep VD significantly. Changes in superficial VD affect VA more. Disease duration is an important factor affecting macular VD.
