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A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy
Published on: July 12, 2021
Toxin-Induced Seizures ∗Adapted from "Toxin-Induced Seizures" in Neurologic Clinics, November 2020
Haley N Phillips1, Laura Tormoehlen2
1Department of Neurology, Emory University, Emory University Brain Health Center, 12 Executive Park Dr. 2 nd Floor, Suite 250, Atlanta, GA 30329, USA.
Abstract:
New toxins are constantly emerging within society. We review common toxins that cause seizure, their mechanisms, associated toxidromes, and treatments. Stimulants, cholinergic agents, gamma-aminobutyric acid (GABA) antagonists, glutamate agonists, histamine and adenosine antagonists, and withdrawal states are highlighted. Understanding current mechanisms for common toxin-induced seizures can promote understanding of future toxins and predicting if seizure may occur as a result of toxicity.
