Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Spongy Bone01:09

Spongy Bone

5.6K
All bones comprise an outer layer of compact bone, and an interior made up of spongy bone tissue, also called cancellous or trabecular bone. In long bones, spongy bone tissue is mainly found in the interior of the epiphyses (broad ends of the bone).
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...
5.6K
Compact Bone01:27

Compact Bone

13.2K
Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
13.2K
Bone Structure01:55

Bone Structure

49.1K
Within the skeletal system, the structure of a bone, or osseous tissue, can be exemplified in a long bone, like the femur, where there are two types of osseous tissue: cortical and cancellous.
49.1K
Bone Remodeling01:40

Bone Remodeling

38.6K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
38.6K
Fractures: Bone Repair01:27

Fractures: Bone Repair

3.8K
Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
3.8K
Bone Markings01:26

Bone Markings

6.5K
Bones have various surface features that help form joints and attach to other soft tissues. Depending on the function, bone markings are categorized into articulating projections, processes for attachment, depressions, and openings.
Articulating Projections
Articulating projections are found where two bones meet to form a joint. These structures are usually found at the ends of bones. The largest articulation is a rounded projection called the head, supported by a narrow neck at the ends of...
6.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical, Safety, and Engineering Perspectives on Wearable Ultrasound Technology: A Review.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control·2023
Same author

Correction for Spatial Averaging Artifacts for Circularly-Symmetric Pressure Beams Measured with Membrane Hydrophones.

IEEE International Ultrasonics Symposium : [proceedings]. IEEE International Ultrasonics Symposium·2022
Same author

Hydrophone Spatial Averaging Artifacts for ARFI Beams from Array Transducers.

IEEE International Ultrasonics Symposium : [proceedings]. IEEE International Ultrasonics Symposium·2022
Same author

AAPM Task Group 241: A medical physicist's guide to MRI-guided focused ultrasound body systems.

Medical physics·2021
Same author

Radiological Society of North America/Quantitative Imaging Biomarker Alliance Shear Wave Speed Bias Quantification in Elastic and Viscoelastic Phantoms.

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine·2021
Same author

Broadband characterization of plastic and high intensity therapeutic ultrasound phantoms using time delay spectrometry-With validation using Kramers-Kronig relations.

The Journal of the Acoustical Society of America·2018
Same journal

Mammalian Respiratory Chain Complex Assemblies and Their Links to Mitochondria Stress-Induced Human Diseases.

Advances in experimental medicine and biology·2026
Same journal

Enzyme Assemblies in Nucleotide Metabolism: Structure, Regulation, and Disease Implications.

Advances in experimental medicine and biology·2026
Same journal

The Pyruvate Dehydrogenase Complex: A 90-Year-Old Enigma Shaping the Future of Structural Enzymology.

Advances in experimental medicine and biology·2026
Same journal

Regulation of the Anti-termination RNA Transcription Complex by Lon-Mediated Lambda N Degradation.

Advances in experimental medicine and biology·2026
Same journal

PCNA Macromolecular Complexes: PCNA Serves as a Molecular Hub Regulating Multiple Cellular Processes Inside and Outside of the Nucleus.

Advances in experimental medicine and biology·2026
Same journal

Dynamic Assemblies in Genome Maintenance.

Advances in experimental medicine and biology·2026
See all related articles

Related Experiment Video

Updated: Sep 24, 2025

Assessment of Bone Fracture Healing Using Micro-Computed Tomography
12:04

Assessment of Bone Fracture Healing Using Micro-Computed Tomography

Published on: December 9, 2022

2.0K

Scattering in Cancellous Bone.

Keith Wear1

  • 1United States Food and Drug Administration, Silver Spring, MD, USA. Keith.Wear@fda.hhs.gov.

Advances in Experimental Medicine and Biology
|May 4, 2022
PubMed
Summary
This summary is machine-generated.

Ultrasonic scattering models validated in human bone reveal diagnostic potential. Backscatter parameters offer valuable insights into bone status in adults and neonates, especially at higher frequencies.

Keywords:
Cancellous boneScattering

More Related Videos

Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model
06:59

Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model

Published on: September 8, 2023

2.7K
Outer-Boundary Assisted Segmentation and Quantification of Trabecular Bones by an Imagej Plugin
09:36

Outer-Boundary Assisted Segmentation and Quantification of Trabecular Bones by an Imagej Plugin

Published on: March 14, 2018

9.5K

Related Experiment Videos

Last Updated: Sep 24, 2025

Assessment of Bone Fracture Healing Using Micro-Computed Tomography
12:04

Assessment of Bone Fracture Healing Using Micro-Computed Tomography

Published on: December 9, 2022

2.0K
Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model
06:59

Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model

Published on: September 8, 2023

2.7K
Outer-Boundary Assisted Segmentation and Quantification of Trabecular Bones by an Imagej Plugin
09:36

Outer-Boundary Assisted Segmentation and Quantification of Trabecular Bones by an Imagej Plugin

Published on: March 14, 2018

9.5K

Area of Science:

  • Biomedical Engineering
  • Medical Physics
  • Orthopedics

Background:

  • Theoretical models for ultrasonic scattering in cancellous bone are validated in vitro.
  • Multiple scattering is less significant than single scattering below 1 MHz but detectable.
  • Higher frequencies (>1 MHz) show more pronounced multiple scattering effects.

Purpose of the Study:

  • To review advancements in ultrasonic scattering research in cancellous bone over the past decade.
  • To highlight the diagnostic utility of backscatter parameters in bone assessment.

Main Methods:

  • Validation of theoretical ultrasonic scattering models in human cancellous bone.
  • In vivo assessment of scattering metrics.
  • Analysis of clinical trial data on backscatter parameters.

Main Results:

  • Clinical trials demonstrate the diagnostic value of backscatter parameters in adults and neonates.
  • Evidence of multiple scattering has been observed, particularly at higher ultrasonic frequencies.

Conclusions:

  • Ultrasonic scattering, especially backscatter parameters, provides crucial diagnostic information for bone status.
  • Continued research in ultrasonic scattering holds promise for improved non-invasive bone assessment.