In vitro activity of tedizolid and linezolid against multidrug-resistant Mycobacterium tuberculosis: a comparative
Akio Aono1, Yoshiro Murase1, Kinuyo Chikamatsu1
1Department of Mycobacterium Reference and Research, The Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association, Kiyose, Japan.
Diagnostic Microbiology and Infectious Disease
|May 21, 2022
Abstract:
The effects of tedizolid (TZD) against multidrug-resistant Mycobacterium tuberculosis isolates were investigated. This is possibly the first study to evaluate the MIC of TZD against Japanese Mycobacterium tuberculosis isolates. As TZD had a significantly lower MIC than LZD (P < 0.01), it was suggested to be a better, non-toxic alternative to LZD.
