Accelerating multi-echo chemical shift encoded water-fat MRI using model-guided deep learning

To accelerate chemical shift encoded (CSE) water-fat imaging by applying a model-guided deep learning water-fat separation (MGDL-WF) framework to the undersampled k-space data.

A model-guided deep learning water-fat separation framework is proposed for the acceleration using Cartesian/radial undersampling data. The proposed MGDL-WF combines the power of CSE water-fat imaging model and data-driven deep learning by jointly using a multi-peak fat model and a modified residual U-net network. The model is used to guide the image reconstruction, and the network is used to capture the artifacts induced by the undersampling. A data consistency layer is used in MGDL-WF to ensure the output images to be consistent with the k-space measurements. A Gauss-Newton iteration algorithm is adapted for the gradient updating of the networks.

Compared with the compressed sensing water-fat separation (CS-WF) algorithm/2-step procedure algorithm, the MGDL-WF increased peak signal-to-noise ratio (PSNR) by 5.31/5.23, 6.11/4.54, and 4.75 dB/1.88 dB with Cartesian sampling, and by 4.13/6.53, 2.90/4.68, and 1.68 dB/3.48 dB with radial sampling, at acceleration rates (R) of 4, 6, and 8, respectively. By using MGDL-WF, radial sampling increased the PSNR by 2.07 dB at R = 8, compared with Cartesian sampling.

The proposed MGDL-WF enables exploiting features of the water images and fat images from the undersampled multi-echo data, leading to improved performance in the accelerated CSE water-fat imaging. By using MGDL-WF, radial sampling can further improve the image quality with comparable scan time in comparison with Cartesian sampling.