Related Experiment Video
Updated: Sep 21, 2025

Retroductal Nanoparticle Injection to the Murine Submandibular Gland
Published on: May 3, 2018
Submandibular Gland Basal Cell Adenoma
Mohamad Najib Salleh1, Abdul Azim Al-Abrar Ahmad Kailani1, Nik Fatin Amirah Nik Min2
1Department of Otorhinolaryngology-Head & Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia Health Campus, 16150 Kota Bharu, Kelantan, Malaysia.
Basal cell adenoma (BCA), a rare salivary gland tumor, was diagnosed preoperatively via fine needle aspiration cytology in a submandibular gland case. Histopathology confirmed the diagnosis, highlighting the importance of this method for rare tumors.
Area of Science:
- Oncology
- Pathology
- Otorhinolaryngology
Background:
- Basal cell adenoma (BCA) is a rare, benign epithelial tumor primarily affecting salivary glands, with a predilection for the parotid gland and rare occurrences in the submandibular gland.
- Accurate diagnosis of BCA is challenging due to its histological similarity to other benign and malignant salivary and non-salivary neoplasms, often necessitating definitive histopathological examination.
Observation:
- This report details a rare case of basal cell adenoma in the submandibular gland of a 60-year-old female patient presenting with painless swelling.
- Preoperative diagnosis was achieved using fine needle aspiration cytology.
- Surgical intervention was performed without complications, and subsequent histopathological analysis confirmed the diagnosis of basal cell adenoma.
Findings:
- Fine needle aspiration cytology can be a valuable tool for the preoperative diagnosis of submandibular gland basal cell adenoma.
- Histopathological examination remains the gold standard for confirming basal cell adenoma, especially given its potential to mimic other salivary gland tumors.
Implications:
- This case underscores the utility of fine needle aspiration cytology in the diagnostic workup of rare salivary gland tumors.
- Accurate preoperative diagnosis can aid in surgical planning and patient management for basal cell adenomas.
- Further research into distinguishing features of BCA on cytology may improve diagnostic accuracy and reduce the need for invasive biopsies.
Related Concept Videos
Exocrine Glands: Unicellular and Multicellular Glands
Exocrine Glands: Types of Secretions
Serous glands produce watery secretions rich in digestive enzymes and proteins. The constituent cells of the serous gland have centrally located nuclei and eosinophilic secretory granules in the cytoplasm. The parotid gland is an example of a serous gland. It secretes saliva, which contains enzymes, such as lipases and...
Salivary Glands and Saliva
Classification of Epithelial Tissues: Glandular Epithelium
Multicellular glands are formed during early development when epithelial budding...
Exocrine Glands: Methods of Secretion
Merocrine Secretion
Merocrine secretion is the most common type of exocrine secretion. The secretions are enclosed in vesicles and moved to the cell's apical surface, where the contents are released by exocytosis. For example, mucous, a watery secretion rich in the glycoprotein mucin, is a merocrine secretion. The eccrine...

